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dr. Herawati Sudoyo, M.S., Ph.D

Herawati Sudoyo

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Herawati Sudoyo is a Senior Scientist and Principal Investigator ofthe Human Genome Diversity and Disease Division at the MochtarRiady Institute for Nanotechnology (MRIN) since 2022. Before joining MRIN, she held the position as the Deputy Director of the Eijkman Institute for Molecular Biology in Jakarta from 1992-2021 as well as the team leader of Human Genome Diversity and Disease and Forensics DNA laboratory. She is the chairperson of Medical Science Commission of the Indonesian Academy of Sciences. Dr.Sudoyo received an Honorary Associate Professor from Sydney Medical School, The University of Sydney, Australia. 

Dr.Sudoyo received her Medical Degree (MD) from the University of Indonesia and earned a PhD in Biochemistry and Molecular Biology from Monash University, Australia. Her research primarily focuses on the molecular pathology of mitochondrially associated disorders, ranging from rare to complex diseases. As part of efforts to enhance forensic science in Indonesia, she contributed to the identification process following the 2004 Australian Embassy bombing, which led to the establishment of the first Forensic DNA Laboratory. With Indonesia's rich ethnic and genomic diversity, she leads the Indonesian Genome Diversity Project (IGDP), generating vast whole genome sequencing data to study population structure, disease susceptibility, and distribution, advancing precision medicine.

 Dr. Sudoyo is a founding member of the Asia Pacific Society of Human Genetics (APSHG). Additionally, she serves on the advisory boards for the Indonesian Society of Human Genetics (InaSHG) and the Indonesian Genomic Association (AGI). She is also a founding member and the first president of the Indonesian Biorisk Association, whereshe continues her expertise and serves on the advisory board. 

 Dr. Sudoyo was actively involved in biosecurity and global health diplomacy, representing Indonesia in various international forums, including the United Nations Biological Weapons Convention (BWC) Meetings of Experts in Geneva (2008-2015) and ASEAN workshops on biological threat reduction. She played a key role in developing Indonesia's National Code of Conduct on Biosecurity and later served as a consultant for the World Health Organization's Science Division on Dual Use Research of Concern in 2020. 

Her contributions to science have been widely recognized, earning her several awards, including the Australian Alumni Award for Scientific Research and Innovation (2008), the Australian Alumni of the Year (2020), the Habibie Award for Medical Science and Technology (2008), the US CDC National Center for Emerging and Zoonotic Infectious Diseases Honor Award for leading the successful multinational partnership to build the first capacity in Indonesia for identifying emerging zoonotic viruses (2016), UNESCO/Third World Academy of Science (TWAS) fellowship on Human Genome Program, and the Toray


Contact  : herawati.sudoyo@mrinstitute.org

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Publication :

1. Ibeh, N., Kusuma, P., CrennaDarusallam, C., Malik, S. G., Sudoyo, H., McCarthy, D. J., & Gallego Romero, I. (2024). Profiling genetically driven alternative splicing across the Indonesian archipelago. American Journal of Human Genetics.

2.  Budhiparama, N., Lumban-Gaol, I., Sudoyo, H., Magetsari, R., & Wibawa, T. (2023). The role of genetic polymorphisms of interleukin-1 (IL-1R1 and IL-1RN) in primary knee osteoarthritis in Indonesia. Scientific Reports.

3. Taufik, L., Teixeira, J., Llamas, B., Sudoyo, H., Tobler, R., & Purnomo, G. (2022). Human genetic research in Wallacea and Sahul: Recent findings and future prospects. Genes, 13(2373).

4. Ekawati, L., Arif, A., Hidayana, I., Nurhasim, A., Munziri, M., Lestari, K., ... &Elyazar, I. (2022). Mortality among healthcare workers in Indonesia during 18 months of COVID-19. PLOS Global Public Health, 2, e0000893.

5. Tanjung, C., Harris, C., Demmelmair, H., Dwitya, S., Munasir, Z., Sudoyo, H., ... &Koletzko, B. (2022). Novel interactions of myristic acid and FADS3 variants predict atopic dermatitis among Indonesian infants. Nutrients, 14(4676).

6. Noviyanti, R., Carey-Ewend, K., Trianty, L., Parobek, C., Puspitasari, A., Balasubramanian, S., ... & Lin, J. (2022). Hypnozoite depletion in successive Plasmodium vivax relapses. PLOS Neglected Tropical Diseases, 16, e0010648.

7. Febinia, C., Malik, S., Djuwita, R., Weta, I., Wihandani, D. M., Maulida, R., ... & Holmes, A. (2021). Distinctive microbiome type distribution in a young adult Balinese cohort may reflect environmental changes associated with modernization. Microbial Ecology, 83.

8. Karmin, M., Flores, J. R., Saag, L., Hudjashov, G., Brucato, N., Crenna-Darusallam, C., ... & Cox, M. (2022). Episodes of diversification and isolation in Island Southeast Asian and Near Oceanian male lineages. Molecular Biology and Evolution, 39.

9. Budhiparama, N., Lumban-Gaol, I., Sudoyo, H., Magetsari, R., & Wibawa, T. (2022). Interleukin-1 genetic polymorphisms in knee osteoarthritis: What do we know? A meta-analysis and systematic review. Journal of Orthopaedic Surgery, 30.

10. Lansing, J. S., Jacobs, G. S., Downey, S. S., Norquest, P. K., Cox, M. P., Kuhn, S. L., ... & Kusuma, P. (2022). Deep ancestry of collapsing networks of nomadic hunter–gatherers in Borneo. Evolutionary Human Sciences, 4, e9.

11. Natri, H., Hudjashov, G., Jacobs, G., Kusuma, P., Saag, L., Crenna-Darusallam, C., ... & Banovich, N. (2021). Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries. American Journal of Human Genetics, 109.

12. Brandt, J. R., Saidah, S. H., Zhao, K., Ishida, Y., Apriyana, I., Ryder, O. A., ... & Roca, A. L. (2021). Characterization of 29 polymorphic microsatellite markers developed by genomic screening of Sumatran rhinoceros (Dicerorhinussumatrensis). BMC Research Notes, 14, 119.

13. Teixeira, J. C., Jacobs, G. S., Stringer, C., Tuke, J., Hudjashov, G., Purnomo, G. A., ... & Helgen, K. (2021). Widespread Denisovan ancestry in Island Southeast Asia but no evidence of substantial superarchaic hominin admixture. Nature Ecology & Evolution, 5.

14. Brucato, N., André, M., Tsang, R., Saag, L., Kariwiga, J., Sesuki, K., ... & Ricaut, F. (2021). Papua New Guinean genomes reveal the complex settlement of North Sahul. Molecular Biology and Evolution, 38.

15. Purnomo, G., Mitchell, K., O'Connor, S., Kealy, S., Taufik, L., Schiller, S., ... & Tobler, R. (2021). Mitogenomes reveal two major influxes of Papuan ancestry across Wallacea following the Last Glacial Maximum and Austronesian contact. Genes, 12(965).

16. Teixeira, J., Jacobs, G., Stringer, C., Tuke, J., Hudjashov, G., Purnomo, G., ... & Helgen, K. (2021). Widespread Denisovan ancestry in Island Southeast Asia but no evidence of substantial super-archaic hominin admixture. Nature Ecology & Evolution, 5.

17. Bobowik, K., Syafruddin, D., Darusallam, C. C., Sudoyo, H., Wells, C., & Gallego Romero, I. (2021). Transcriptomic profiles of Plasmodium falciparum and Plasmodium vivax-infected individuals in Indonesia. bioRxiv.

18. Kusuma, P., Brucato, N., Cox, M., Nuraini, C., Letellier, T., Grangé, P., ... & Ricaut, F. (2021). A genomic perspective of the origin and dispersal of the Bajau sea nomads in Indonesia. Journal of Ethnic History.

19. Pedro, N., Brucato, N., Fernandes, V., André, M., Saag, L., Pomat, W., ... & Ricaut, F. (2020). Papuan mitochondrial genomes and the settlement of Sahul. Journal of Human Genetics, 65.

20. Natri, H. M., Bobowik, K. S., Kusuma, P., Darusallam, C. C., Jacobs, G. S., Hudjashov, G., ... & Romero, I. G. (2020). Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago. PLoS Genetics, 16(5), e1008749.

21. Büking, R., Cox, M. P., Hudjashov, G., Saag, L., Sudoyo, H., & Stoneking, M. (2020). Archaic mitochondrial DNA inserts in modern day nuclear genomes. BMC Genomics, 21(1), 55.

22. Wall, J. D., Stawiski, E., Ratan, A., Kim, H. L., Kim, C., Gupta, R., ... & Peterson, A. S. (2019). The GenomeAsia 100K Project enables genetic discoveries across Asia. Nature, 576, 106-111.

23. eXu, S., Purnomo, G. A., Jinam, T. A., Azuma, F., &Aghakhanian, F. (2019). Dissecting human genetic diversity in Asia with a special focus on Indonesia. Frontiers in Genetics, 10, 164.

24. Matsumoto, H., Sukmawati, M., Herawati, L., Wahyuningsih, R., Tanjung, C., Sudoyo, H., ... & Suda, A. (2019). Analysis of population structure of Indonesian ethnic groups and its implications on genome-wide association studies. Journal of Human Genetics, 64(6), 545-553.

25. Nurhasanah, A., Setiadi, G., Sudoyo, H., & Tsang, R. (2018). Investigating the genetic origins of the Malay people: Insights from genome-wide SNP data. Annals of Human Genetics, 82(5), 336-344.

26. Aditya, S., Hudjashov, G., Karafet, T., Lansing, J. S., Sudoyo, H., & Cox, M. P. (2018). Mitochondrial DNA diversity and the demographic history of the Indonesian archipelago. BMC Evolutionary Biology, 18, 139.

27. Purnomo, G. A., Kusuma, P., Karafet, T., Sudoyo, H., & Cox, M. P. (2017). A genomic survey of natural selection and adaptive differentiation in the Indonesian archipelago. Molecular Biology and Evolution, 34(12), 3041-3053.