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SOP for Involving Animal Subject

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Title

Writing, Reviewing, Distributing and Amending Standard Operating Procedures

Preparation of Guidelines

Constituting an Ethics Committe

Confidentiality / Conflict of Interest Agreement

Training Personnel and EC Members

Selection of Independent Consultants

Management of Protocol Submissions

Use of Study Assessment Forms

Expedited Review

Initial Review of Submitted Protocols

Review of New Medical Device Studies

Review of Resubmitted Protocols

Review of Protocol Amendments

Management of Progress Report

Review of Final Reports

Intervention in Protocol Deviation /Non-Compliance/Violation

Response to Animals Welfare

Management of Study Termination

Review of Serious Adverse Events (SAE)/Suspected Unexpected Serious Adverse Event (SUSAR) Reports

Site Monitoring Visit ( Post Approval Monitoring & Facilities Inspection and Program Review )

Agenda Preparation, Meeting Procedures and Minutes

Emergency Meeting

Communication Records

Maintenance of Active Study Files

Archive and Retrieval of Documents

Maintaining Confidentiality of MRIN EC Documents

Audit and Inspection of the MRIN EC