Picture1

HBV Project

The Genomic Division is one of the research laboratories in Mochtar Riady Institute for Nanotechnology (MRIN). The specific objectives of this division are: 

  • Synthesizing a particular nucleotide sequence of interest. 
  • Generating a full length or partial DNA sequence of the received samples. 
  • Performing molecular analysis at DNA level.

Currently, we conduct various research projects that focus on long-term resistance mutations profiles of several antiviral nucleotide/nucleoside agents, and predicting liver disease progression associated hepatitis B virus (HBV) in Indonesia based on whole genome sequence. We are collaborating with Klinik Hati Prof. Ali Sulaiman (KHPA) to collect samples from chronic HBV patients with antiviral treatment (follow-up study). Our ongoing research projects are :


The specific objectives of this division are:

  • Investigating Lamivudine and Telbivudine resistant mutation in Indonesian chronic HBV patients treated with Lamivudine (LMV) and Telbivudine (LdT). 
  • Investigating Tenofovir resistant mutation in Indonesian chronic HBV patients treated with Tenofovir (TDF). 
  • Investigating several specific and novel mutations in Indonesian chronic HBV patients for predicting liver disease progression. 
  • Developing HBV detection method using personal glucose meter (PGM).

Members of Genomic Division

Principal Investigator:
Dr. rer. nat. Ivet Suriapranata.


Research Assistant:
Venansi Viktaria S.Si
Rury Mega Wahyuni, drh., M.Si.