Chelzie Crenna


Position             : Research Assistant

Qualifications   :

                               - B.Sc. in Biotechnology (Atma Jaya Catholic University of Indonesia)

                               - M.Biotech in Biotechnology (Atma Jaya Catholic University of Indonesia) 


Profile                :

                                Chelzie Crenna-Darusallam has been many projects, related to marine biodiversity (DNA barcoding and bioprospecting) and pharmacogenetic study relate to the malaria drug treatments in collaborate with Malaria unit of the Eijkman Insitute for Molecular Biology. She was admitted into a 3-month internship program at Charles Darwin University, Australia, in 2010 for Fish DNA Barcoding project and Research Visitor for a year contract at Nanyang Technological University, Singapore in 2015 for the Indonesia Genome Diversity Project.                              

Interests            :  

                               - Human genetic diversity and disease epidemiology

                               - Pharmacogenetics/genomics

                               - Functional genomics

Awards              :


Contact             :  chelzie.crenna@mrinstitute.org

Publications     :  

1.Episodes of Diversification and Isolation in Island Southeast Asian and Near Oceanian Male Lineages. 

   Molecular Biology and Evolution, Volume 39, Issue 3, March 2022, msac045, https://doi.org/10.1093/molbev/msac045

2.Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries.

    American journal of human genetics, 109(1), 50–65. https://doi.org/10.1016/j.ajhg.2021.11.017

3.Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago.

    PLoS genetics, 16(5), p.e1008749.

4.Multiple Deeply Divergent Denisovan Ancestries in Papuans.

    Cell, 177(4), 1010–1021.e32. https://doi.org/10.1016/j.cell.2019.02.035

5.Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium            vivax Malaria.JAMA network open, 1(4), e181449. https://doi.org/10.1001/jamanetworkopen.2018.1449

6.The clinical and public health problem of relapse despite primaquine therapy: case review of repeated relapses of Plasmodium vivax acquired in Papua New             Guinea.Malaria journal, 13, 488. https://doi.org/10.1186/1475-2875-13-488