drh. Safarina G Malik, M.S, Ph.D.


       Malik is a Principal Investigator of the Genome Diversity and Diseases Laboratory at Mochtar Riady Institute of Nanotechnology. Before joining MRIN, she was the Principal Secretary of the Eijkman Institute, as well as the head of the Genome Diversity and Diseases Laboratory and the head of the National Genome Center at the Eijkman Institute. She was the principal investigator for mitochondria and lifestyle diseases research activities. Malik supervises a wide range of projects, including Nutrigenomics/Nutrigenetics, malaria in pregnancy, gut microbes studies, and association study of genetic diversity and diseases. From 2020 to 2021, she also led the Genomic Surveillance of SARS-CoV-2 research project at the Eijkman Institute, which had contributed to more than 3,000 submitted whole-genome sequences in GISAD.Malik is actively reviewing research proposals for Risbin Iptekdok and the Indonesian Danone Institute. She also has a long list of experience in reviewing journals, including BMC Research Notes, Cardiovascular Diabetology, and the International Journal of Medicine and Medical Sciences. 

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             * Women Reach Initiative 2013 from Harvard School of Public Health (2013)

             * Visiting Scientist Fellowship 2010 from Centro Studi Fegato, Trieste, Italy (12 February-12 March 2010)

             * TWAS Research Grant (2006)

             * International Mobility Project Fellowship 2006 from AREA Science Park, Trieste, Italy (8 August-4 September 2006)

             * International Genetic Federation (IGF) Travel Bursaries to attend the XIX International Congress of Genetics, Melbourne, Australia (6-11 July 2003)

             * Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) Fellowship to attend the 7th Congress on Advances in Biochemistry                    and Molecular Biology, Sydney, Australia (24-29 September 1995)

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Contact : safarina.malik@mrinstitute.org

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Publications :

1. Whole-Genome Sequencing of SARS-CoV-2 Infection in a Cluster of Immunocompromised Children in Indonesia. Front Med (Lausanne). 2022 Mar 4;9:835998.         doi: 10.3389/fmed.2022.835998. eCollection 2022.

2. COVID-19 prevalence among healthcare workers in Jakarta and neighbouring areas in Indonesia during early 2020 pandemic. Ann Med. 2021 Dec;53(1):1896-           1904. doi: 10.1080/07853890.2021.1975309.

3. The Association of Maternal Vitamin D Status during Pregnancy and Neonatal Anthropometric Measurements: A Longitudinal Study in Minangkabau Pregnant         Women, Indonesia. J Nutr Sci Vitaminol (Tokyo). 2020;66(Supplement):S63-S70. doi: 10.3177/jnsv.66.S63.

4. The Association between Vitamin D-Related Gene Polymorphisms and Serum 25-Hydroxyvitamin D Concentration: A Prospective Cohort Study in Pregnant                 Minangkabau Women, Indonesia. J Nutr Sci Vitaminol (Tokyo). 2020;66(Supplement):S295-S303. doi: 10.3177/jnsv.66.S295.

5. Non-nutritional anemia: Malaria, thalassemia, G6PD deficiency and tuberculosis in Indonesia. Asia Pac J Clin Nutr. 2020;29(Suppl 1):S32-S40. doi:                              10.6133/apjcn.202012_29(S1).04.

6. Maternal biomarker patterns for metabolism and inflammation in pregnancy are influenced by multiple micronutrient supplementation and associated with              child  biomarker patterns and nutritional status at 9-12 years of age. PLoS One. 2020 Aug 7;15(8):e0216848. doi: 10.1371/journal.pone.0216848. eCollection            2020.

7. A genetic approach to study the relationship between maternal Vitamin D status and newborn anthropometry measurements: the Vitamin D pregnant mother          (VDPM) cohort study. J Diabetes Metab Disord. 2020 Jan 27;19(1):91-103. doi: 10.1007/s40200-019-00480-5. eCollection 2020 Jun.

8. Obesity in the Balinese is associated with FTO rs9939609 and rs1421085 single nucleotide polymorphisms. PeerJ. 2020 Jan 3;8:e8327. doi:                                        10.7717/peerj.8327. eCollection 2020.

9. Sex-linked genetic diversity originates from persistent sociocultural processes at microgeographic scales. R Soc Open Sci. 2019 Aug 28;6(8):190733. doi:                 10.1098/rsos.190733. eCollection 2019 Aug.

10. Vitamin D deficiency status and its related risk factors during early pregnancy: a cross-sectional study of pregnant Minangkabau women, Indonesia. BMC                 Pregnancy Childbirth. 2019 May 22;19(1):183. doi: 10.1186/s12884-019-2341-4.

11. Obesity risk and preference for high dietary fat intake are determined by FTO rs9939609 gene polymorphism in selected Indonesian adults. Asia Pac J Clin               Nutr. 2019;28(1):183-191. doi: 10.6133/apjcn.201903_28(1).0024.

12. Placental mitochondrial DNA copy number is associated with reduced birth weight in women with placental malaria. Placenta. 2019 May;80:1-3. doi:                          10.1016/j.placenta.2019.03.005. Epub 2019 Mar 15.

13. Polymorphisms of Aldose Reductase (ALR2) Regulatory Gene are Risk Factors for Diabetic Retinopathy in Type-2 Diabetes Mellitus Patients in Bali, Indonesia.        Open Ophthalmol J. 2018 Oct 18;12:281-288. doi: 10.2174/1874364101812010281. eCollection 2018.

14. Increased mitochondrial DNA copy number in maternal peripheral blood is associated with low birth weight in Lombok, Indonesia. Placenta. 2018 Oct;70:1-3.           doi: 10.1016/j.placenta.2018.08.001. Epub 2018 Aug 9.

15. Placental weight ratio affects placental mRNA expression of insulin-like growth factor-I and long isoform of the leptin receptor in Plasmodium                                       falciparuminfected pregnant women. Asia Pac J Clin Nutr. 2016 Dec;25(Suppl 1):S75-S82.

16. From 'lactose intolerance' to 'lactose nutrition'.

17. Uncoupling protein 2 gene polymorphisms are associated with obesity. Cardiovasc Diabetol. 2012 Apr 25;11:41. doi: 10.1186/1475-2840-11-41.

18. Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study. BMC Res         Notes. 2011 May 27;4:167. doi: 10.1186/1756-0500-4-167.